Tag Archive | "Mesothelioma"

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Mesothelioma Variants


Mesothelioma is a rare yet deadly cancer that almost always surfaces in a malignant form and results in tumors on significant organs of the body. Most people believe mesothelioma is a cancer of the mesothelium. So what exactly is the mesothelium? The mesothelium is a film or sac that surrounds vital organs in an attempt to protect them such organs can include the lungs and heart. Mesothelioma can almost always be attributed to asbestos. While we might think there exists only one form of mesothelioma, there actually several. We will be talking about pleural mesothelioma, peritoneal mesothelioma, and pericardial mesothelioma. As unfortunate as it may be, mesotheliomas symptoms dont surface until the disease has progressed, which at times can be several years following exposure to asbestos. As one might guess, this can make diagnosis a pain and treatment a near impracticality.

Pleural mesothelioma is the widely known variant of mesothelioma. In this form of mesothelioma, tumors develop on the lining of the lungs. Most people with the disease have a difficult time swallowing, breathing, and getting around without coughing. They may also experience other symptoms such as weight loss.

Peritoneal Mesothelioma is a more uncommon form of mesothelioma. This variant of the disease sheds ill will on the lower parts of the body, particularly the abdomen and stomach. This cancer can start in either of the two locations and metastize grow into other parts of the body. This variant of the disease tends to bring about more severe symptoms such as nausea and blood clots. Since these tumors can put pressure on surrounding organs, they can make for an unpleasant sensation.

Finally, its time we talk of a very rare type of mesothelioma, pericardial mesothelioma. This variant focuses on the heart and can bring about palpitations and breathing problems.

If you are or have ever experienced these types of symptoms, its best to speak to a doctor.

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What is mesothelioma


“Mesothelioma” is the term used to describe a cancerous tumor that involves the mesothelial cells of an organ. Mesothelial cells are cells that form a protective lining over the lungs, heart and abdominal organs. The most common type of mesothelioma is pleural mesothelioma. The pleura is a thin membrane found between the lungs and the chest cavity. It provides a lubricated surface so that the lungs do not rub and chafe against the chest walls.
What causes it?
Virtually all cases of mesothelioma are related to inhaling of asbestos fibers. There are about 3,000 cases per year mostly men over the age of 40 and there will be about 300,000 cases before 2030. Mesothelioma usually spreads rapidly through the mesothelial cells to the heart and abdominal organs. The life span is typically 24 months after diagnosis, but it depends on what stage the cancer is detected, the health of the patient and other factors.
Although asbestos exposure causes mesothelioma, it has a latency period after exposure that could last 15 to 50 years. This means that someone who worked in a factory with asbestos 40 years ago could be developing mesothelioma now. Anyone who knows they were exposed to loose asbestos fibers should be tested regularly for mesothelioma.

Diagnosis
The onset of mesothelioma is usually very slow. The first symptom is a constant pain in the chest. This pain is later accompanies by difficulty breathing due to an accumulation of fluid in the chest. Other symptoms include coughing, fever and weight loss. Mesothelioma can be diagnosed by your doctor with a chest CT-scan.

Prognosis the outcome
Mesothelioma advances in 4 stages
Stage I – the tumor is limited to the area of the lining of the lung and usually limited to only one side of the chest.
Stage II – the tumor extends to other organs within the chest cavity, such as the heart or lymph nodes in the chest.
Stage III – the tumor expands to the other side of the chest or it spreads into the abdominal organs. The lymph nodes outside the chest are affected.
Stage IV -the cancer spreads to different parts of the body far outside the chest area liver, brain, bone, etc….

Mesothelioma is an extremely deadly disease. The average survival time is about one year from date of diagnosis. About 20 of patients who find their cancer early and treat it aggressively will reach the five-year mark.
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Who is at Risk for Mesothelioma?


Mesothelioma, the deadly disease which has topped news headlines for the last decade, is contracted through exposure to airborne fibers of asbestos. Sadly, the under-regulation of asbestos usage in years past, and arguably still today, exposed millions to airborne fibers and as a result thousands contracted the disease.

It can be safely said that almost everyone in the world has been exposed to asbestos in varying degrees. Because of the unique nature of the disease, even those who have suffered only minimal exposure are at risk of contracting the disease. In effect, virtually everyone has some risk of contracting Mesothelioma.

But this sort of statement perhaps oversteps the bounds of rationality. While it is certainly true that individuals who have been exposed to small amounts of asbestos for relatively short periods of time have contracted the disease, this is a rarity rather than a regularity. In fact, the vast majority of Mesothelioma cases involve individuals who were exposed to airborne asbestos fibers for intense and extended periods of time.

The industries most in danger of prolonged exposure and thus of contraction are shipbuilding trades, asbestos mining and milling, textile manufacturing, insulation work in construction, and brake repair personnel. There are, however, some other minor factors which can affect the likelihood of contracting the disease. Among these is radiation exposure. There have been causes in which individuals who were exposed to radiation have subsequently displayed signs of and ultimately contracted mesothelioma. However, empirical studies to attempt to verify this correlation have not proven out this claim very strongly.

Another more certain cause of the disease was the taking of the Polio vaccine between 1955 and 1963. Some batches of this vaccine were contaminated with Simian Virus 40 which has been detected in a host of rare cancers including Mesothelioma.

Those involved in construction or who lived in homes in the Cappadocian region of Turkey are also particularly at risk. In this region, homebuilders used Erionite, which is a type of zeolite silica stone. Exposure to the fibrous strands of this building material have led to an annual death rate of roughly 1 of the population which dies of mesothelioma each year in Turkey.

One of the most influential factors affecting Mesothelioma contraction is genetics. Some individuals who have been exposed to long periods and high quantities of asbestos have not contracted the disease. As a result, doctors have concluded that genetics play a major role in determining whether or not patients contract the disease. Unfortunately, the gene variability which offers some resistance to the disease also means that some are particularly vulnerable to asbestos exposure.

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Mesothelioma Surgery


Mesothelioma is a rare, deadly form of cancer which can occur in a number of types. Mesothelioma is caused by exposure to asbestos, a group of natural fibres which are extremely dangerous if inhaled as fibres. When fibres are inhaled they become lodged in the alveoli of the lungs and over a period of time these fibres make tissue and cells abnormal and cause mesothelioma cancer. Pleural mesothelioma is the most common form of mesothelioma cancer, accounting for approximately 75 of all mesothelioma cases. The next most common form, peritoneal mesothelioma, accounts for 20 of all mesothelioma cases and pericardial mesothelioma accounts for the remaining 5. Pleural mesothelioma affects the lining of the lungs, peritoneal mesothelioma attacks the peritoneum, which is the lining of the abdomen and pericardial mesothelioma affects the tissue surrounding the heart. All three of these types of cancer occur in extremely important areas of the human body and this is one of the reasons why it is so difficult to treat. Treatment methods such as radiation therapy can only be conducted with strict radiation dosage restrictions due to the possibility of damaging a vital organ such as the lungs or the heart.

Aggressive mesothelioma surgery is undertaken only by the strongest of mesothelioma patients because weaker patients are at risk of death within the first month after the operation. An experienced doctor will evaluate a patient before deciding that surgery is the best treatment method. He will take into account age, medical record, disabilities, allergies, sex, even weight. The operation will then take place. Mesothelioma surgery consists of cutting open a patient and removing the majority of cancerous cells from either the lining of the lungs, abdomen or heart in an attempt to gain long term control over the cancer. Due to the proximity of the cancer to major organs of the body, the operation can only be performed by extremely skilled surgeons. There is a chance that a patient will die during the operation.

A second type of mesothelioma surgery is called palliative procedures. This is a far less dangerous and aggressive form of surgery which does not attempt to gain long term control over the cancer. Palliative procedures are designed to lessen the symptoms for a patient when it is almost certain that the patient will die inevitably from the cancer.

Mesothelioma surgery can also be coupled with radiation therapy and chemotherapy in what is known as dual therapy. Patients would undergo surgery to get rid of the majority of the cancerous mesothelioma cells and then chemotherapy and radiation therapy would be used to kill off any remaining cells. This combination of treatments has proved to be effective and has one of the highest success rates for treatments of mesothelioma cancer.

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Symptoms of Mesothelioma


The term Mesothelioma in medical terms is defined as form of cancer that proliferates at a very fast rate after it has been diagnosed, which affects the mesothelial cells in the body. After detailed study of this disease by several scientists all over the world, it has been concluded that in most of the cases the reason is the direct contact with loose asbestos particles. This disease is generally known to be derived from an abnormality that arises from inhaling the loose asbestos particles suspended in the air for a very long time. The chances of the patients, diagnosed of mesothelioma, have very bleak chances of survival which is not more than one or two years and if it has been detected long back and rigorous medication has been started on the patient then the patient is likely to live for about five years.

There are three types of mesothelioma but the symptoms of the diseases depend on their kinds. The symptoms vary from one-another but the general symptoms that are found in patients suffering from different types of mesothelioma are weight loss, chest pain, loss of appetite, short breath , plain cough and cough with blood. Diagnosing mesothelioma in its initial stages is not possible because symptoms surface very late and that, these symptoms are no special signs indicating the particular disease but are common for other diseases too.

Generally the symptoms of mesothelioma resemble to that to any other normal lung diseases. Most of the symptoms arise in the lungs, where the mesothelial cells covering the lungs and the cavity between them are affected due to prolonged inhalation of asbestos fibers. Consulting with the physician is very necessary from time to time and necessary test must be conducted to detect the disease.

The main symptom of mesothelioma is a constant pain in the chest which is followed by short breaths and difficult breathing because of accumulation of fluid in the chest, which makes breathing all the more difficult. Some of the other symptoms of the disease include abnormalities in the lungs, which can be diagnosed under proper supervision of the doctor with a chest CT-scan.

Basically, the disease of mesothelioma advances in four stages. In the first stage, begins the formation of the tumor in the area of lining of the lung and doesnt exceed from one side of the lung. And then in the second stage the tumor extends to other organs in the chest cavity, such as heart. Then in the third stage its extents to the other abdominal organs affecting all the other organs too. Finally in the fourth and the last stage the tumor extends to all parts of the body and affects all the parts adversely. These are some of the symptoms of the disease of mesothelioma, by which the disease can be tracked in the initial stages of its occurrence.

DISCLAIMER This information is not presented by a medical practitioner and is for educational and informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read.
Since natural andor dietary supplements are not FDA approved they must be accompanied by a two-part disclaimer on the product label that the statement has not been evaluated by FDA and that the product is not intended to diagnose, treat, cure or prevent any disease.

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Mesothelioma The Basics


Mesothelioma is a rare form of cancer that is usually found in those previously exposed to asbestos. Cancerous cells form in the mesothelium, which is a protective lining that covers most of the bodys internal organs. These cells typically form in the lining of the lungs, abdomen, or the sac that encircles the heart.

The average life span of a person diagnosed with the disease is about 4 to 24 months from the finding. About 3,000 people in the U.S. die of mesothelioma every year. People at risk are those who have been previously exposed to asbestos dust, including former steel workers, auto mechanics, mineworkers, and military workers, among many others. Their family members may also be at risk, as the asbestos dust from clothing can travel through the air.

Mesothelioma has an extremely long latency period, which means that symptoms of the disease may not emerge until 30 to 50 years after the initial exposure to asbestos. Pleural mesothelioma, which is the most common type and affects the area around the lungs, may cause shortness of breath, chest pains, and a persistent cough, which may lead to coughing up blood. These symptoms are caused by the build up of fluid between the lining of the lung and the chest cavity. The disease may start in the chest area and spread to other areas of the body. Other symptoms of pleural mesothelioma include weight loss, severe breathing trouble, fever, difficulty swallowing, and swelling of the face and neck areas. It should be noted that some people with the disease do not experience any serious symptoms at all.

Peritoneal mesothelioma is rarer than pleural mesothelioma, and affects the abdominal area. Symptoms of peritoneal mesothelioma include abdominal swelling and pain due to the build up of fluid in the abdominal cavity, nausea, loss of appetite, and vomiting. Breathing complications and chest pains may also be present, as well as bowel obstruction, anaemia, fever, and blood clotting.

The rarest form of the disease is pericardial mesothelioma, which first forms in the area surrounding the heart. Tumors grow in the tissues around the heart and spread from there. Chest pain, shortness of breath, constant coughing, and shivering may be symptoms of this form of mesothelioma.

Diagnosis of the disease is oftentimes difficult, due to the fact that the symptoms associated with mesothelioma are similar to those of other conditions. The symptoms of the disease become more serious as the cancerous tumors enter the later stages of development, so people who have been exposed to asbestos at any time in their lives should contact their doctor immediately. Even if a person has never been exposed directly to asbestos but is experiencing any of the above symptoms, they should inform their doctor as soon as possible, as asbestos dust and fibres may have traveled through the air from items such as clothing.

People who have been diagnosed with any form of mesothelioma should immediately contact a lawyer. Individual states have their own statutes of limitation, meaning that there is a set time limit regarding how long a patient has to act on their diagnosis. When searching for a lawyer to handle your case, be sure to find one that has prior experience with mesothelioma cases. They will have the contacts and resources to take care of your case in a timely manner. The Internet is a helpful and efficient resource for a mesothelioma lawyer search.

Patients do not have to be concerned with paying lawyers up-front, since the majority of mesothelioma lawyers work on a contingency fee basis, which means that they will not request payment of any kind unless they successfully settle your case. Lawyers will usually take a 35 cut of whatever settlement or reward the patient receives, but patients seeking compensation for their disease have nothing to lose and everything to gain in going to a lawyer for help.

The average mesothelioma-related settlement in the U.S. is 1 million. Cases that go to trial average awards of approximately 6 million, according to the RAND Corporation. A bill called the Fairness in Asbestos Injury Resolution Act of 2005 FAIR Act of 2005 introduced on March 17, 2005, seeks to create set amounts of compensation for mesothelioma victims, which would depend on their symptoms.

People who have mesothelioma are able to seek large compensation amounts because their disease is a result of a companys decision not to take sufficient measures to protect its workers from breathing in asbestos while on the job.

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Malagnant Mesothelioma


Malignant mesothelioma is an uncommon, but no longer rare, cancer that is difficult to diagnose and poorly responsive to therapy. Malignant mesothelioma is the most serious of all asbestos-related diseases.
A layer of specialized cells called mesothelial cells lines the chest cavity, abdominal cavity, and the cavity around the heart. These cells also cover the outer surface of most internal organs. The tissue formed by these cells is called mesothelium.

The mesothelium helps protect the organs by producing a special lubricating fluid that allows organs to move around. For example, this fluid makes it easier for the lungs to move inside the chest during breathing. The mesothelium of the chest is called the pleura and the mesothelium of the abdomen is known as the peritoneum. The mesothelium of the pericardial cavity the “sac-like” space around the heart is called the pericardium
Tumors of the mesothelium can be benign noncancerous or malignant cancerous. A malignant tumor of the mesothelium is called a malignant mesothelioma. Because most mesothelial tumors are cancerous, malignant mesothelioma is often simply called mesothelioma.

Mesothelioma was recognized as a tumor of the pleura, peritoneum and pericardium in the late 1700′s. However it was not until much later, in 1960, that this particular type of tumor was described in more detail and even more importantly, its association with asbestos exposure was recognized. The first report linking mesothelioma to asbestos exposure was written by J.C.Wagner, and described 32 cases of workers in the “Asbestos Hills” in South Africa. Since than the relationship between mesothelioma and asbestos exposure has been confirmed in studies around the world.
The incidence of mesothelioma in the United States remains very low, with 14 cases occurring per million people per year. Despite these numbers the noticed threefold increase in mesothelioma in males between 1970 and 1984, is directly associated with environmental and occupational exposure to asbestos, mostly in areas of asbestos product plants and shipbuilding facilities.

Although the disease is much more commonly seen in 60-year old men, it has been described in women and early childhood as well. The cause of the disease is not so well understood in these latter two groups, but there is some evidence of possible asbestos exposure for some of these cases as well
Mesothelioma is one of the deadliest diseases known to man; the average life span of an inflicted person from the time of diagnosis until death is less than 24 months. It’s a disease that strikes approximately 3,000 United States citizens each and every year; hard working people who have labored for a lifetime to provide for their families, doing the work that keeps this country running and a great place to live. They worked in factories, at shipyards, in mines, for the US military, as engineers, as pipefitters, as steel workers, as auto mechanics, and in so many other professions. They came home to their loved ones exhausted and covered in dirt and dust; tired, but content that they had a job and were providing for their family. Content that they were putting food on the table and a house over their loved one’s heads. Content that they were working to make a better life for their families in this generation and the next…
But what they didn’t know was that while they were working so hard, they were not only slowly killing themselves, but those that they were working so hard to help; their family, their loved ones.

What is the mesothelium?

The mesothelium is a membrane that covers and protects most of the internal organs of the body. It is composed of two layers of cells One layer immediately surrounds the organ; the other forms a sac around it. The mesothelium produces a lubricating fluid that is released between these layers, allowing moving organs such as the beating heart and the expanding and contracting lungs to glide easily against adjacent structures.
The mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women

What Is My Diagnosis?
There are three types of mesothelioma. Pleural mesothelioma is a cancer of the lining of the lung pleura, peritoneal mesothelioma is a cancer of the lining of the abdominal cavity peritoneum, and pericardial mesothelioma is a cancer of the lining surrounding the heart pericardium. Sub-types or cell types of mesothelioma are epithelioid the most common, and considered the most amenable to treatment, sarcomatous a much more aggressive form, and biphasic or mixed a combination of both of the other cell types.
The structural appearance of cells under the microscope determine the cell or sub-type of mesothelioma. Epithelioid is the least aggressive; sarcomatoid, the most aggressive. The biphasic or mixed cell type shows structural elements of both of the other two.

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Pericardial Mesothelioma FAQ


What is pericardial mesothelioma?

Pericardial Mesothelioma is a rare form of mesothelioma cancer that accounts for approximately 5 of all mesothelioma cases. Cancerous cells build up on the lining of the heart.

What is the cause of pericardial mesothelioma?

Asbestos is the main cause of pericardial mesothelioma. When exposed to asbestos without sufficient protection, dust and fibres from the asbestos are inhaled and become lodged in the lungs. From here they can either pass into the lymphatic system and get transported to the lining of the heart or the fibres can just pass through to the heart over time.

Who is at risk from pericardial mesothelioma?

Those who have worked with asbestos constantly for a period of time without sufficient protection are those at risk. These people include construction workers and those who work in asbestos manufacturing plants. Individuals in contact with those in contact with asbestos are also at risk because asbestos fibres can cling to clothes and hair.

How much exposure to asbestos does it take to have a possibility of getting pericardial mesothelioma?

This varies depending on the concentration of the asbestos dust and fibres in the area but it has been recorded that those who have only been exposed for a couple of months have a chance of obtaining pericardial mesothelioma.

What are the symptoms of pericardial mesothelioma?

Common symptoms of pericardial mesothelioma are persistent coughing, coughing up blood, shortness of breath, chest pain and palpitations. Other symptoms that patients may experience are weight loss, nausea and loss of appetite.

What is the latency period of pericardial mesothelioma?

All forms of mesothelioma have an extraordinarily long latency period amount of time symptoms take to show up after having disease. The latency period is between 30 50 years and so pericardial mesothelioma is usually discovered in elderly men who have had pericardial mesothelioma for most of their life but have never known it.

What is the prognosis for pericardial mesothelioma?

This is highly dependent on how early and how aggressively the cancerous cells are treated. If the cancer is treated when it has fully developed and matured then the chances of a patients survival is very small. The prognosis could be only a couple of months.

Is there any promising research for pericardial mesothelioma?

At the moment, research into pericardial mesothelioma is being conducted all over the USA in research labs and also many pharmaceutical companies are endeavouring to find new drugs for chemotherapy. So far, there is still no cure for mesothelioma although researchers predict that new drugs will soon be discovered.

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The Link Between Asbestos Exposure and Smoking


It is common knowledge that smoking is hazardous to ones health. Additionally, many people know that exposure to asbestos is very dangerous and can lead to the development of the disease mesothelioma. What many people do not know, however, is that when smoking and asbestos exposure are combined, both of the harmful elements work together to create a much higher risk for the development of mesothelioma, or other types of cancers.

Cigarettes have many harmful chemicals that break down the lungs and can be leading causes in cancer. Asbestos exposure also exposes the lung to harmful chemicals that weaken your bodys defenses against cancers and other lung problems. Studies have found that cigarette smokers have a four to eleven times greater chance of getting lung cancer than non-smokers. If a person is a heavy smoker, than the number goes up to twenty-seven times as likely. Adding a heavy smoker to asbestos exposure sends the probabilities for lung cancer skyrocketing. In fact, heavy smokers with a history of asbestos exposure have a 50 to 90 times greater chance of having lung cancer. Needless to say, heavy smoking and large amounts of asbestos exposure will almost certainly lead to lung cancer.

Smoking causes chronic obstructive pulmonary disease COPD. People who smoke and have been exposed to asbestos have higher occurrences of COPD than people who have not been exposed to asbestos. Some of the terrible effects of COPD are the inflammation and eventual destruction of small airways in the lung tissue. Once these tissues have been destroys, some people can be completely debilitated.

Studies have shown that people who quit smoking, but still had asbestos exposure are less likely to have lung cancer than those people who continue to smoke. Some say that COPD can be reversed the longer time is spent without smoking. Additionally, people who are able to quit smoking often feel healthier over time and significantly increase their life expectancy. Even though any amount of smoking or asbestos exposure can lead to lung cancer, the sooner one quits, the better off he or she will be.

Asbestos exposure is very harmful for anyone. However if you know that you have been exposed to asbestos, and continue to smoke, you are playing with fate. The sooner someone stops smoking, the sooner his or her lungs can begin to heal. Mesothelioma and other cancers are very serious diseases that often end in death. In order to stay alive for loved ones, smokers should quit immediately.

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Asbestos – Mesothelioma


Asbestos is the biggest work place killer today. Those who have worked with asbestos or who are regularly in contact with someone who has are at risk from asbestosis, lung cancer and mesothelioma. All these are fatal respiratory diseases which are extremely difficult to cure. Research is being carried out in various research labs all over the USA and many pharmaceutical companies are also endeavouring to find new drugs and treatment methods.

One rare disease caused by asbestos which is becoming increasingly common is mesothelioma. Although unknown by many today, it is almost certain that awareness of this disease will be broadcasted worldwide because of its increasing occurrence in men aged between 55 and 70. Many of these men are now lodging multi million dollar lawsuits against the companies who subjected them to asbestos. Those most at risk from mesothelioma are those who have been in regular contact with asbestos dust and fibres without sufficient protection. Just a couple of months of exposure to asbestos can lead to mesothelioma 30 years later. The latency period amount of time the disease takes to start taking effect of mesothelioma is 30 – 50 years which is one of the reasons it is so difficult to cure because it is very difficult to tackle in its early stages. Another reason it is so difficult to cure is that its early symptoms are characteristic of many other more common diseases such as pneumonia.

Mesothelioma symptoms include

- Chest pains
- Coughing that worsens over time
- Weight loss
- Shortness of breath
- Coughing up blood
- Nausea and vomiting
- Fatigue
- Wheezing
- Lung infection
- Swollen lymph nodes
- Loss of appetite

A patient will feel symptoms depending on which type of mesothelioma he or she has got. For information on the different types of mesothelioma go to

In the next 35 years it is estimated that over 1 million people will die from asbestos related diseases in developed countries. Most of these people will die from lung cancer and mesothelioma as these two are the most prolific asbestos related diseases.

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